CPR Therapeutics Inc. has completed early-phase proof-of-principal studies of its integrated cardiopulmonary resuscitation (CPR) system. These studies, undertaken at the Halperin Cardiology Bioengineering Laboratory at the Johns Hopkins Hospital, confirmed the Company’s foundational concept that multiple CPR pump mechanisms can be combined to produce dramatic improvements in hemodynamics.
Norman Paradis MD, the Company’s Founder and CEO stated: “We are pleased that these early studies provided such a strong signal of efficacy. Hemodynamic improvements of this magnitude are unheard of in resuscitation research. They strongly indicate that we’re on the right track and that our human prototype system will have a positive clinical trial.” Dr. Paradis is an emergency medicine physician and Professor at the Geisel School of Medicine at Dartmouth.
Dr. Henry Halperin, the Company’s Chief Scientific Officer: “This is very exciting. While the hypothesis that multiple CPR pump mechanisms might be synergistically combined had face-validity, it is good to see actual data.” Dr. Halperin is a cardiologist and the David J. Carver Professor of Medicine at Johns Hopkins University.
In a widely used model of cardiac arrest, the Company’s multimodal CPR resulted in more than 50% improvements in indicators of vital organ perfusion.
Dr. Paradis added “improvements like this are predictive of significantly increased rates of successful resuscitation. We look forward to continuing with our prototype R&D and moving toward clinical trials.”
CPR Therapeutics Inc.
CPR Therapeutics Inc. is a seed-stage medical device company developing the next generation system for cardiopulmonary resuscitation.
Sudden cardiac arrest may be the largest single cause of death and years of lost life in Western countries. Improving the outcome of patients after cardiac arrest is one of the great unmet medical needs. Each year over 300,000 deaths occur following sudden cardiac arrest in the U.S. alone. Fifty years after the first description of modern cardiopulmonary resuscitation (CPR) survival is below 10%, and the standard-of-care for these patients remains manual chest compressions performed by rescuers with their hands.
CPR Therapeutics Inc. is developing the first advanced technology automated CPR system that integrates and synchronizes multiple technological innovations into a single system that can be easily applied under emergency conditions. This advanced technology multimodal CPR cannot be performed by humans. It will enhance blood flow and the efficacy of electrical countershock in ways previously only available in laboratory settings. This system will, for the first time, demonstrate clinically significant improved survival. Info@CPRTherapeutics.com
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